Assessment of the Antiadertional Potential of Pogostemon cablin Essential Oil against Staphylococcus aureus

• DOI: 10.24018/ejmed.2023.5.5.1850
• Publication Date: 2023-10-12T14:11:47Z
• Authors: Samara Crislâny A...; Danilo Nogueira Maia; Clara Martins Maia; Joana Darc Silva ...; Elizandra Silva d...; Gymenna Maria Ten...; Camila Helena Mac...; Veneziano Guedes ...; Luanna Abílio Dín...; Gyselle Tenório G...; Raline Mendonça d...; Abrahão Alves de ...
• Keywords: 0301 basic medicine; 03 medical and health sciences; 3. Good health

Nosocomial pneumonia, an infection of the lung parenchyma caused by bacterial species, corresponds to a morbidity responsible for reducing the quality of life and further compromising the hospitalized patient. Among the bacteria that cause this infection is Staphylococcus aureus, which has proved resistant to the drugs used in its treatment. Therefore, the need for new studies is urgent and phytotherapy has been gaining space. The objective of this research was to evaluate the anti-adherent activity of Pogostemon cablin essential oil against a strain of Staphylococcus aureus. To obtain the Minimum Inhibitory Adherence Concentration (MIC), Muller Hinton broth with 5% sucrose was used, the Sa 101 strain of the bacterial species under study, as well as, the positive control with 0.12% chlorhexidine. The material was incubated at 37 °C for 24 hours for reading using fuchsin. Through analysis, it was found that the oil studied was able to inhibit the adhesion of bacteria to the wall of the tube at a concentration of 1:2, showing positive activity against the formation of biofilm by Staphylococcus aureus, although the result found is lower than that of chlorhexidine, which inhibited at a ratio of 1:8. It is concluded that Pogostemon cablin oil showed anti-adherent activity against the strain under study, however, inferior when compared to the positive control.