Antimicrobial activity of polyphenols extracted from Thai medical plants on extended-spectrum beta-lactamase-producing Escherichia coli isolates from healthy dairy cows

• DOI: 10.24425/pjvs.2022.142038
• Publication Date: 2023-11-06T12:41:27Z
• Authors: A. Konputtar; W. Aengwanich; B. Saraphol; M. Yossapol
• Keywords: Broth microdilution

Escherichia coli producing extended-spectrum beta-lactamase (ESBL) are antimicrobial- -resistant Enterobacteriaceae important in the livestock production sector, especially dairy cows because these antimicrobial-resistant bacteria can be transferred to consumers via consumption. If antimicrobials continually used farms, this may result antimicrobial resistance. Therefore, investigation of resistance and finding new alternative methods for inhibiting ESBL-producing E. is essential. Hence, aim study was examine ability selected inhibit ATCC 25922, control isolated from farms. We also investigated capacity polyphenol extract 10 varieties medicinal plants using a broth microdilution method. It found that were susceptible all agents, i.e., ampicillin, cefotaxime, ciprofloxacin, chloramphenicol, gentamycin, imipenem, nalidixic acid, tetracycline, sulfamethoxazole/ trimethoprim. However, exhibited both susceptibility antimicrobials. The extracted Psidium guajava Linn at lowest concentration 4.5 mg/mL, which could bacteria, but same not coli. These phenomena indicated had Polyphenol, non-resistant coli,