Evaluation of the clinical efficacy of racecadotril in the treatment of neonatal calves with infectious diarrhea

• DOI: 10.24425/pjvs.2023.148276
• Publication Date: 2023-12-12T11:43:12Z
• Authors: B. Tras; M. Ok; M. Ider; T.M. Parlak; R. Yildiz; H. Eser Faki; Z. Ozdemir Kutahya; K. Uney

Neonatal calf diarrhea (NCD) is one of the most important concerns in cattle production.Escherichia coli bacterial agent NCD.Although vaccination and antibiotic treatment are common NCD, high antigenic diversity E. increase resistance cause difficulties control.The study aimed to investigate rate diarrhea, isolate an NCD strain, determine antimicrobial resistance, find out about some surface antigens.Fecal samples (n=115) were analyzed pathogenic strains with nine mixed infections; sixty-one from fifty diarrhoeic calves.Among isolates diseased animals, 22 K99+STa+F41, 3 K99+STa, F41, 2 Stx1, strain K99, eae, Stx2+eae detected.27 F17-associated fimbriae have been identified.17 F17a, 6 F111, F17c, carrying F17a F17c gene regions, whereas subfamily typing could not be performed.Serotypes determined by molecular serological methods: 32/61 (52.5%) O101 2/61 (3.3%) O9 serotypes.But 27 serotypes detected.The profiles disc diffusion method.The rates antibiotics trimethoprim-sulphamethoxazole 91.7%, ampicillin 86.7%, enrofloxacin gentamicin 45%, tobramycin 41.7%, cefotaxime 3.3%, ceftazidime 1.7%.Due increasing prophylaxis gaining importance.In further research, structures should examined detail, it form basis for vaccine hyperimmunization studies developed.