Combined antimicrobial action of streptomycin and terpenes against atypical mycobacteria isolated from fish

• DOI: 10.24425/pjvs.2024.149334
• Publication Date: 2024-03-20T14:40:35Z
• Authors: L. Guz; K. Puk; D. Szwajgier; A. Pastuszka
• Keywords: Terpene; Nerol; Antimycobacterial; Isoeugenol

The aim of this study was to investigate the antimycobacterial activity 39 free terpenes and their in combination with streptomycin. Antimicrobial first evaluated by screening at concentrations from 1.56 400 μg/mL. None these exhibited positive effects against any nontuberculous mycobacteria (NTM) strains tested. However, six (isoeugenol, nerol, (+)-α-terpineol, (1R)-(−)-myrtenol, (+)-terpinen-4-ol, eugenol) were shown enhance streptomycin NTM isolated diseased ornamental fish.