Insulin resistance and abomasal motility disorders in cows detected by use of abomasoduodenal electromyography after surgical correction of left displaced abomasum

• DOI: 10.2460/ajvr.2004.65.1319
• Publication Date: 2006-01-23T18:32:19Z
• Authors: Davide Pravettoni; Klaus Doll; Markus Hummel; Elena Cavallone; Michela Re; Angelo G. Belloli
• Keywords: Blood Glucose; 2. Zero hunger; 3-Hydroxybutyric Acid; Hydrocortisone; Electromyography; Abomasum; Stomach Diseases; Cattle Diseases; 04 agricultural and veterinary sciences; Fatty Acids, Nonesterified; Glucagon; 0403 veterinary science; Animals; Insulin; Cattle; Female; Insulin Resistance; Gastrointestinal Motility

Abstract Objective —To determine the correlation between insulin concentrations and myoelectrical activity of abomasum in cows with a left displaced (LDA). Animals —14 dairy an LDA at onset lactation. Procedure —During surgical correction LDA, 3 pairs electrodes were placed smooth muscle gastrointestinal tract (abomasal body, pars pylorica, duodenum) each cow. Electromyographic recordings obtained once per day for 7 days. Samples collected tested to insulin, glucagon, cortisol, glucose, β-hydroxybutyrate, nonesterified fatty acids. Results —All 14 cattle had high glucose time admission, independent ketosis. Concentrations decreased slowly after treatment associated progressive increase abomasoduodenal myoelectric activity. The allocated into 2 groups (suspected insulinresistant cattle, n = 7; suspected non–insulin-resistant 7) on basis persistent hyperinsulinemia during postoperative period. Seven days surgery, patterns still significantly lower cows, compared cows. Conclusions Clinical Relevance —Insulin resistance appears be common LDA. Analysis results this study reveals that abomasal atony depends persistence serum insulin. could provide explanation pathogenetic factor LDAs frequent relapses affected by condition. ( Am J Vet Res 2004;65:1319–1324)