Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission

• DOI: 10.2460/javma.1988.193.10.1259
• Publication Date: 2025-02-06T18:36:33Z
• Authors: J. P. Dubey; A. L. Hattel; D. S. Lindsay; M. J. Topper
• Keywords: Neospora; Paresis; Direct fluorescent antibody

Neospora caninum infection was diagnosed in 5 young dogs from 2 litters with a common parentage. The pups were born healthy, but developed hind limb paresis to 8 weeks after birth. predominant lesions polyradiculoneuritis and granulomatous polymyositis. seen microscopically sections of naturally infected pups, isolated cell cultures, mice, inoculated canine tissues. Antibodies N detected sera by indirect fluorescent antibody test.