Inheritance of associated ocular and skeletal dysplasia in Labrador Retrievers

• DOI: 10.2460/javma.1988.193.10.1269
• Publication Date: 2025-02-06T18:36:58Z
• Authors: C. B. Carrig; D. P. Sponenberg; G. M. Schmidt; H. W. Tvedten
• Keywords: Inheritance

Summary A breeding colony was established to investigate the inheritance of associated ocular and skeletal dysplasia in Labrador Retrievers; 124 pups were produced. These evaluated for presence lesions, including cataracts, vitreous strands, persistent hyaloid remnants, retinal folds, dysplasia, peripapillary hyperreflectivity, rhegmatogenous detachments, abnormality, which recognized by shorter than normal forelimbs an abnormal morphologic appearance radius ulna. Analysis distribution lesions indicated that syndrome is caused one gene, has recessive effects on skeleton incompletely dominant eye. This would suggest suspect carrier dogs could be identified test matings with a known homozygote.