Use of ketoconazole in the treatment of canine nasal aspergillosis

• DOI: 10.2460/javma.1989.194.06.782
• Publication Date: 2025-02-06T18:42:51Z
• Authors: Nicholas J. H. Sharp; Martin Sullivan
• Keywords: Dogs; Ketoconazole; Dose-Response Relationship, Drug; Aspergillus fumigatus; Thiabendazole; Nose Diseases; Animals; Aspergillosis; Dog Diseases

Summary Fifteen dogs with nasal aspergillosis were treated ketoconazole (5 mg/kg of body weight, q 12 h, po ) for 2 to 18 weeks. Four whose conditions deteriorated during treatment received less than the prescribed 6 Six months or more later, only 47% determined be disease-free, on basis no fungal growth culture. It was concluded that at this dosage is a useful canine aspergillosis, but effective thiabendazole.