Comparison of three treatment regimens for sheep and goats with caseous lymphadenitis

• DOI: 10.2460/javma.234.9.1162
• Publication Date: 2009-05-01T07:05:26Z
• Authors: Kevin E. Washburn; Wesley T. Bissett; Virginia R. Fajt; Melissa C. Libal; Geoffrey T. Fosgate; Joseph A. Miga; Kristine M. Rockey
• Keywords: Caseous lymphadenitis

Abstract Objective —To compare the effectiveness of 3 treatment regimens for small ruminants with caseous lymphadenitis. Design —Randomized clinical trial. Animals —44 client-owned sheep and goats. Procedures —Aspirates were obtained from 48 lesions 44 enrolled animals submitted bacterial culture. randomly assigned to 1 groups. Treatment group A (n = 15 lesions) consisted opening, draining, flushing SC administration procaine penicillin G. B closed-system lavage intralesional tulathromycin. C 18 All reexamined approximately month after treatment, unless failure was detected prior that time. Results —43 had positive results ( Corynebacterium pseudotuberculosis ) Proportions resolution infection by did not differ significantly among groups (group A, 13/14 [92.9%]; 95% confidence interval [CI], 69.5% 99.6%; B, 10/12 [83.3%]; CI, 54.9% 97.1%; C, 14/17 [82.4%]; 59.1% 95.3%). Conclusions Clinical Relevance —Acceptable alternatives may exist goats Use tulathromycin in this study constituted extralabel drug use, which would require extended withholding times before milk or meat treated can be sold human consumption.