Biological activity and composition of teas and tinctures prepared from Rosa rugosa Thunb.

• DOI: 10.2478/s11535-011-0105-x
• Publication Date: 2011-12-24T06:56:45Z
• Authors: Marta Olech; Renata Nowak; Renata Los; Jolanta Rzymowska; Anna Malm; Katarzyna Chrusciel
• Keywords: Micrococcus luteus; HeLa

Abstract The study was designed to determine the total phenolic, flavonoid, o-dihydroxyphenol, tannin, and carotenoid content as well antiradical, antitumor antimicrobial properties of two types galenic preparations from Rosa rugosa Thunb. Such extracts obtained various plant parts have not been studied date. Our findings revealed high antiradical activity examined preparations, with root, leaf flower (IC50 ranging 0.27 0.19 mg dry extract per DPPH·) showing greatest potential. MIC MBC values against 8 reference bacterial strains (i.e. Staphylococcus epidermidis, aureus, Bacillus subtilis, Micrococcus luteus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis) were determined. Generally, tinctures found be more active than teas 0.08 2.5 mL−1 0.31 1.25 mL−1, respectively. Anticancer activities ovarian (TOV-112D), cervical (HeLa), breast (T47D) lung cancer (A549) cell lines evaluated using BrdU test. data demonstrate considerable impact polyphenols on anticancer (ethanolic, in particular).