Microinflammation in Patients on Hemodialysis: A Practical Approach

• DOI: 10.2478/sjecr-2021-0047
• Publication Date: 2024-09-11T05:12:53Z
• Authors: Marko Nenadovic; Aleksandra Nikolic; Marijana Stanojev...; Tomislav Nikolic; Dejan Petrovic; Jasna Trbojevic-S...

Abstract Microinflammation is a non-traditional risk factor for the development of cardiovascular diseases in patients on hemodialysis. It occurs 30-50% these patients, and its main causes are: uremic toxins, oxidative stress, metabolic acidosis, vitamin D deficiency, overhydration, altered intestinal microbiome, impaired epithelial barrier integrity, increased translocation endotoxin from lumen into systemic circulation, occult infection vascular approach hemodialysis, periodontal disease, bioincompatibility hemodialysis membrane presence solution. The clinical consequences microinflammation accelerated atherosclerosis, malnutrition, anemia, resistance to action erythropoietin, hemoglobin variability dialysis-related amyloidosis. Postdilution online hemodiafiltration, extended adsorptive prevent microinflammation. Optimal control prevents diseases, improves quality life outcome who are treated with regular