PREVALENCE AND RISK FACTORS OF HYPONATREMIA IN CRITICALLY ILL HOSPITALIZED CHILDREN: AN OBSERVATIONAL STUDY

• DOI: 10.24911/sjp.106-1672832695
• Publication Date: 2024-05-27T02:25:22Z
• Authors: Anita Mehta; Maariya Fatima; Ajeet Yadav
• Keywords: Etiology; Fulminant hepatic failure

Critically ill children frequently encounter a most common and potentially life threatening electrolyte disturbances, i.e. hyponatremia. It is an independent risk factor for prolonged hospitalization in Intensive Care Unit (ICU) increased in-hospital mortality. Hyponatremia occurs up to 20-30% of admissions Pediatric (PICU). This observational study was conducted pediatric intensive care unit (PICU) tertiary hospital developing country from September 2018 2019. Admission criteria our PICU is; need mechanical ventilation, fulminant hepatic failure, vasopressor support, respiratory failure poorly controlled seizure. We studied 256 children, aged 1 month 18 years, with normal serum sodium at admission. In seventy-two (28.1%) developed about two third (n=48, 66.7%) them within 72 hours admission PICU. Maximum (n=46, 63.9%) hyponatremic group were below 5 years. Wasted (n=68, 26.6%) isonatremic 20 (27.8%) 48 (26%) respectively. Most etiology hyponatremia cerebral salt wasting syndrome (CSWS) (n=20, 27.8%) followed by drug induced cases (n=19, 26.4%). Drugs responsible diuretics antileptics. study, multi organ (OR=5.05, 95%CI=1.90-13.43; p=0.0001), shock (OR=7.38, 95%CI=3.56-12.28; use (OR=6.74, 95%CI=3.45-13.17; p=0.0001) coagulopathy 95%CI=3.45- 2 13.17; the factors development Mortality among (44.4%) significantly higher than (21.7%). disturbance found critically patients associated