The influence of glutathione on the prooxidant-antioxidant activity in kidneys and blood of rats with rhabdomyolytic model of acute kidney injury

• DOI: 10.24959/ubphj.16.49
• Publication Date: 2018-04-03T11:23:09Z
• Authors: V. M. Drachuk; I. I. Zamorskii; O. M. Goroshko
• Keywords: Intraperitoneal injection; Glutathione reductase

The influence of glutathione on the prooxidant-antioxidant balance in rats’ kidneys and blood under conditions rhabdomyolytic model acute kidney injury was studied experiment. It is observed that intraperitoneal administration glutathioneіn dose 30 mg/kg normalizes balance, confirmed by reduction lipid protein peroxidation intensity, normalization catalase peroxidase activity, SH-groups andceruloplasmin content.