Food-induced anaphylaxis in early childhood and factors associated with its severity

• DOI: 10.2500/aap.2021.42.210051
• Publication Date: 2021-09-06T16:52:36Z
• Authors: Metin Aydogan; Erdem Topal; Nalan Yakıcı; Hazal Cansu Acar; Zeynep Hızlı Demi...; Mustafa Arga; Pınar Uysal; Sezin Aydemir; Isıl Eser Simsek; Zeynep Tamay; Sükrü Cekic; Ozlem Cavkaytar; Fatih Kaplan; Ayca Kıykım; Müjde Tugba Cogurlu; Ayse Süleyman; Esra Yücel; Emre Akkelle; Gonca Hancıoglu; Adem Yasar; Tuba Tuncel; Hikmet Tekin Naca...; Cigdem Aydogmus; Nermin Güler; Haluk Cokugras; Nihat Sapan; Hasan Yüksel; Recep Sancak; Mehmet Sarper Erd...; Oner Ozdemir; Cevdet Ozdemir; Fazıl Orhan
• Keywords: Interquartile range; Concomitant

Background: Several factors that increase the risk of severe food-induced anaphylaxis have been identified. Objective: We aimed to determine demographic, etiologic, and clinical features in early childhood also any other associated with anaphylaxis. Methods: carried out a medical chart review cases from 16 pediatric allergy immunology centers Turkey. Results: The data 227 patients 266 episodes were included study. median (interquartile range) age first episode was 9 months (6-18 months); 160 these boys (70.5%). mild 75 (28.2%), moderate 154 (57.9%), 37 (13.9%). most frequent food allergens involved cow's milk (47.4%), nuts (16.7%), hen's egg (15.8%). Epinephrine administered only 98 (36.8%) episodes. A logistic regression analysis revealed two statistically significant independently anaphylaxis: presence angioedema hoarseness during anaphylactic episode. Urticaria observed less frequently who developed hypotension. In addition, confusion syncope 25.9- 44.6-fold increases, respectively, concomitant Conclusion: Cow's milk, nuts, caused majority moderate-to-severe patient presents history should alert clinicians reaction may be severe. confusion, syncope, or stridor probably indicates