Methionine imbalance and toxicity in calves.

• DOI: 10.2527/2000.78102722x
• Publication Date: 2016-08-09T20:46:53Z
• Authors: M Abe; H Okada; D Matsumura; H Sato; M Funaba; T Iriki
• Keywords: Male; 2. Zero hunger; Glycine max; Body Weight; 0402 animal and dairy science; 04 agricultural and veterinary sciences; Animal Feed; Methionine; Dietary Supplements; Animals; Homeostasis; Cattle; Dietary Proteins; Amino Acids

The occurrence of methionine imbalance and toxicity was examined using 70- 100-kg Holstein bull calves. animals had been trained to maintain reflex closure the reticular groove after weaning at 5 wk age, Trials 1 (n = 30) 2 24) were conducted on 7 12 respectively. Calves received a corn-soybean meal diet in Trial corn-corn gluten 2. In 1, postruminal administration 6 g DL-methionine/d increased ADG, feed intake, gain/feed, N retention compared with control group receiving N-free supplement. However, did not improve these variables, whereas both 18 24 g/d resulted BW loss decreased gain/feed utilization efficiency. 2, 16 L-lysine from monohydrochloride efficiency 8 addition exert an adverse effect variables. additional supplementation DLmethionine/d negated improvement, 32 These results showed that occurred calves even modest excess DL-methionine, 70-kg more susceptible than Plasma concentrations branched-chain amino acids phenylalanine linearly increasing amounts DL-methionine 0 such decrease mainly within range 1. This suggested occur relation metabolism via transsulfuration pathway.