Stability of Biologically Synthesized Silver Nanoparticles (AgNPs) Using Acalypha indica L. Plant Extract as Bioreductor and Their Potential as Anticancer Agents Against T47D Cells

• DOI: 10.26554/sti.2025.10.1.101-110
• Publication Date: 2025-01-01T14:32:27Z
• Authors: Luailik Madaniyah; Saidun Fiddaroini; Elok Kamilah Hayati; Moh. Farid Rahman; Akhmad Sabarudin
• Keywords: Silver nanoparticle

This work investigates the anticancer potential of silver nanoparticles (AgNPs) against T47D cells as well stability AgNPs manufactured using extract from Acalypha indica L. used a bioreductant. The plant was to produce and stabilize AgNPs, tracked for 30 days UV-Vis spectroscopy Particle Size Analysis (PSA), which included evaluations extended sun exposure. Transmission Electron Microscopy (TEM) characterize size shape nanoparticles, Fourier Transform-Infrared Spectroscopy (FT-IR) determine functional groups were responsible stabilization. Despite gradual increase, remained stable throughout study period. MTT assay confirmed their potent cytotoxicity cells, underscoring indica-derived effective agents cancer therapy, offering promising alternative novel treatments.