NEUROTROPIC ACTIVITY OF PLANT ALKALOIDS

• DOI: 10.26577/eb.2021.v88.i3.14
• Publication Date: 2021-10-08T15:46:44Z
• Authors: R. B. Seydakhmetova; K.D. Rakhimov; D.S. Tutay; T.T. Mukhanova; А. А. Zholbarys; A. Amanzhan; S.M. Adekenov
• Keywords: Harmine; Elevated plus maze

Natural alkaloids are promising compounds for the development of new domestic neurotropic drugs based on them. The article presents results a study effect plant (harmine, delphinifolin, echinopsin, zongoramine). assessment samples was carried out model experimental stress using tests «Open field» and «Raised cross-shaped maze».. As result conducted studies, it found that harmine, echinopsin zongoramin at dose 10 mg / kg exhibit effect, increasing level research activity, reducing anxiety, fear anxiety in animals Field» maze». presence an aryl group molecules zongoramine, is important their activity.