Treatment of neuro-invasive listeriosis: an overview

• DOI: 10.29014/ns.2018.28
• Publication Date: 2019-02-14T12:26:13Z
• Authors: P. Gudeikaitė; J. Valaikienė; R. Mameniškienė
• Keywords: neurolisteriosis; 03 medical and health sciences; 0302 clinical medicine; treatment; encephalitis; meningoencephalitis; Neurology. Diseases of the nervous system; RC346-429; Listeria monocytogenes; 3. Good health

Increasing mortality and morbidity rates of neurolisteriosis in Lithuania Europe require methodological standardized treatment a rapid response to the patient’s serious condition. Listeria monocytogenes is an aerobic gram-positive bacillus that can cause invasive listeriosis humans, which most commonly affects central nervous system. Clinically, occurs as meningoencephalitis, associated with highest rate patients severe conditions. The at-risk populations are pregnant women, neonates, people over 65 years age, chronic diseases or using immunosuppressive drugs. In case suspected acute meningitis, encephalitis meningoencephalitis these individuals, it must be considered pathogen monocytogenes, resistant therapy cephalosporins. First-line recommended combination amoxicillin gentamicin intravenously. If patient allergic beta-lactams, co-trimoxazole recommended. administration dexamethasone against increases rate. article reviews clinical manifestation diagnostic criteria neuroinvasive provides recommendations.