Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report.

• DOI: 10.30476/ijms.2021.89841.2061
• Publication Date: 2022-07-01
• Authors: Neda Rahimian; Nazanin Alibeik; Elham Pishgar; Parisa Dini; Meysam Abolmaali; Zahra Mirzaasgari
• Keywords: myalgia; Nasal congestion; Coronavirus

For a while, coronavirus disease-2019 (COVID-19) has been major global pandemic. It primarily affects the respiratory system but extrapulmonary manifestations such as gastrointestinal and neurological symptoms. Data on myasthenia gravis (MG), complication of COVID-19, are limited. We herein report manifestation ocular MG an initial symptom COVID-19. In November 2020, 31-year-old healthy woman was referred to Firoozgar Hospital (Tehran, Iran) with left upper eyelid ptosis diplopia well general weakness, myalgia, fever, nasal congestion for four days prior admission. Although acetylcholine receptor antibody in her serum negative, increased jitter several muscles led diagnosis MG. Nasal swab reverse transcription-polymerase chain reaction (RT-PCR) assay tested positive severe acute syndrome-coronavirus-2 (SARS-CoV-2) infection. Computed tomography (CT) scan chest revealed bilateral ground-glass opacities some foci consolidation formation, thymus normal. The patient successfully treated remdesivir dexamethasone. eventually discharged good condition improved A limited number studies have suggested possible association between Therefore, further data required substantiate proposed association. Clinicians should be aware during COVID-19 pandemic better diagnose manage patients SARS-CoV-2