Solanum aculeastrum Dunal berries: Phytochemical profiling and GC-MS analysis of methanolic extract and n-hexane, dichloromethane, ethyl acetate and n-butanol fractions

• DOI: 10.30574/ijsra.2024.11.1.0250
• Publication Date: 2024-02-18T03:27:30Z
• Authors: Gift Crucifix Pe...; Bernard Guyah; Peter G. Mwitari; Inyani John L. Lagu; Mercy Jepkorir; James H Ombaka
• Keywords: Dichloromethane; Phytochemical; Hexane

Background: Solanum aculeastrum is reportedly used in several diseases including gonorrhea, bronchitis, jigger infestations and wounds, cancers. We conducted an exhaustive phytochemical GC-MS profiling of its methanol extract solvents’ fractions. Methods: About 4500g dried berries S. was extracted with methanol, part which partitioned into fractions n-hexane, dichloromethane, ethyl acetate, n-butanol aqueous These fractional preparations were subjected to except fraction. Results: The percentage yield 430.69g S.aculeastrum 9.57%w/w, while the yields 19.4g 38.4g DCM, 6.4g 81.03g 21.2g freeze-dried 7.08%w/w, 14.03 %w/w, 2.33%w/w, 29.60%w/w 7.74%w/w respectively. relative presence glycosides, alkaloids, tannins, flavonoids, terpenoids, phenols, saponins confirmed quinones. identified 32 compounds alkane, alcohol, carbohydrate, fatty acids, glycerides, vitamins some unclassified compounds. 25 alkene, vitamin n-hexane DCM fraction yielded 20 isoprenoid, amino carboxylic acid 22 acetate phenol, glycerolipid 11 fluorinated aromatic substance, hormonal antineoplastic a non-steroidal anti-inflammatory agent. Conclusion: This study has further elaborated on bioactive aculeastrum, aid robust understanding pharmacologic activities.