Formulation and evaluation of mouth dissolving film of antihypertensive agentFormulation and evaluation of mouth dissolving film of antihypertensive agent

• DOI: 10.30574/wjarr.2022.16.2.1251
• Publication Date: 2022-12-07T01:51:32Z
• Authors: Swati Saxena; Abhishek Patel; Sarang Kumar Jain
• Keywords: Folding endurance

Mouth dissolving film is the one of most advanced oral solid dosage form because its flexibility and comfort in use. films are that disintegrate dissolve within a minute when placed mouth without taking water or chewing. This allows medication to bypass first pass metabolism so bioavailability may be improved .Mouth has potential improve onset action lower dosing eliminate fear chocking. Formulation involves both visual performance characteristics as plasticized hydrocolloids, API taste masking agents being laminated by solvent casting semisolid method. Solvent method preferred over other methods it offers great uniformity thickness prepared having fine glossy look better physical properties. evaluated for various parameters like thickness, property folding endurance, disintegration dissolution time. review gives an idea about formulation techniques, evaluation parameters, overview on packaging some available marketed products films.