Problems in differential diagnosis of mycosis fungoides and psoriasis: comparison of clinical and morphological features

• DOI: 10.31088/cem2022.11.3.73-80
• Publication Date: 2022-10-19T11:36:00Z
• Authors: V.A. Smolyannikova; ; A.E. Karamova; ; A.A. Vorontsova; ; L.F. Znamenskaya; ; M.A. Nefedova; ; K.M. Aulova
• Keywords: CD5; Peripheral T-cell lymphoma; Cutaneous T-cell lymphoma

Mycosis fungoides is an epidermotropic primary cutaneous T-cell lymphoma, represented com-posed of small and medium-sized lymphocytes with cerebriform nuclei. Differential diagnosis lymphoma chronic autoimmune dermatoses, including psoriasis, may present significant chal-lenges in some cases. We analyzed three clinical cases mycosis fungoides, which psoriasis was initially diagnosed. Histological immunohistochemical studies a wide panel antibodies (CD4 CD8, CD2, CD5, CD7, CD3) were performed, monoclonal T-lymphocyte populations determined PCR. propose algorithm for diagnosing fungoides. Keywords: morphology, immunohistochemistrycal study,