The Role of Asymmetric Dimethyl Arginine and Oxidant/Antioxidant System in Preeclampsia

• DOI: 10.3109/15513815.2011.618869
• Publication Date: 2011-11-07T14:10:32Z
• Authors: Hasan Alacam; Z. Gunnur Dikmen; Halil Yaman; Erdinc Cakir; Ozgur Deren; E. Ozgur Akgul; Ibrahim Aydin; Yasemin Gulcan Kurt; Ugur Keskin; Sukran Akalin; Belgin Polat; Nuri Danisman; Pakize Dogan
• Keywords: Malondialdehyde; Endothelial Dysfunction

Preeclampsia is a syndrome characterized by hypertension and proteinuria. The aim of this study to find the relationship between preeclampsia, asymmetric dimethyl arginine (ADMA), oxidant/antioxidant system. Twenty-one preeclamptic 28 normal pregnant women were included in study. In cord bloods, ADMA parameters measured. Asymmetric levels significantly increased pregnancies compared control group (p = 0.006). activities antioxidant enzymes malondialdehyde < 0.001, p 0.022, respectively). Development endothelial dysfunction oxidative stress may play role developing preeclampsia.