Inhibitory Control Development from Infancy to Early Childhood: A Longitudinal fNIRS Study

• DOI: 10.31234/osf.io/qs4uv_v2
• Publication Date: 2025-02-14T15:28:33Z
• Authors: Abigail Fiske; Alicia Mortimer; Liam H Collins-Jones; Carina de Klerk; Sylvia Gattas; Henrik Dvergsdal; Gaia Scerif; Karla Holmboe
• Keywords: Neurophysiology and neuropsychology; Executive function; QP351-495; Response inhibition; Prefrontal cortex; Functional near-infrared spectroscopy; Parietal cortex

The developmental period from infancy to early childhood is one of substantial change – in advancements in cognitive skills, such as early executive functions, but also in the maturation of the prefrontal and parietal cortices that parallel such advances. The current study aims to investigate the emergence and development of inhibitory control, a core executive function, from infancy to early childhood. We collected longitudinal functional near-infrared spectroscopy (fNIRS) data from the same sample of participants at 10-months, 16-months, and 3½ years of age whilst they completed the Early Childhood Inhibitory Touchscreen Task. In our previous publications, we reported that 10-month-old infants recruited right lateralised regions of the prefrontal and parietal cortex when inhibition was required. Despite no change in response inhibition performance, 16-month-olds recruited broader and bilateral regions of the prefrontal and parietal cortex. Results of the current study found that 3½-year-olds activated regions of the right inferior parietal cortex and the right inferior frontal gyrus when inhibition was required. Response inhibition performance was significantly improved by early childhood, yet there was commonality in the brain regions recruited at 16-months and 3½ years. This could suggest that these brain regions are fundamental neural indices of inhibitory control, even from toddlerhood.