Assessment of the Association of Chlamydia e pneumoniae Infection with Lung Cancer in a Moroccan Patients’ Cohort

• DOI: 10.31557/apjcp.2023.24.2.659
• Publication Date: 2023-02-28T13:47:41Z
• Authors: Meryem Chebak; Maryame Azzouzi; Houda Chaibi; Meryem Fakhkhari; Ichrak Benamri; Malika Mguil; Khadija Hajjout; Adil Zegmout; Nabil Tiresse; Ismail Rhorfi; Hicham Souhi; Ahmed Abid; Rachida Zahraoui; Jamal Bourkadi; Hicham Oumzil; Fouzia Radouani; Khalid Sadki
• Keywords: Association (psychology)

Background: Chlamydia pneumoniae (C. pneumoniae) is a respiratory pathogen associated with chronic inflammatory and its detection in human lung cancer suggests involvement cancerogenesis. Our study aimed to evaluate the association between C. infection Lung Cancer disease Moroccans patients control cohorts, through molecular investigation. Methods: The comprised 42 43 healthy controls. All participants provided demographics, Clinical, Toxic behaviors datas, peripheral blood sample for testing, Nested Polymerase Chain Reaction (PCR) was performed Deoxyribonucleic acid (DNA) detection. Statistical analysis using IBM®SPSS®software. Results: Positive PCR results cases controls were respectively 33.3% 4.7%, there by significant difference identified (p <0.05). Data also showed that tobacco could act synergically as risk factor of cancer. In fact shown alcohol use < 0.05). Conclusion: potentially primary Moroccan population has combined effects Tabaco consumption.