Maslinic acid derived from olive fruit in combination with resistance training improves muscle mass and mobility functions in the elderly

• DOI: 10.3164/jcbn.18-104
• Publication Date: 2019-03-06T22:36:37Z
• Authors: Narumi Nagai; Satomi Yagyu; Anna Hata; Shinsuke Nirengi; Kazuhiko Kotani; Toshio Moritani; Naoki Sakane
• Keywords: Nutritional Supplementation

Maslinic acid, derived from olive fruit, reduces pro-inflammation cytokines, which are involved in muscle fiber atrophy. Therefore, the maslinic acid ingestion may enhance muscular response to resistance training through anti-inflammatory action. We therefore conducted a parallel, double-blind, randomized, placebo-controlled trial that examined whether combination of supplementation and improve mobility functions community-dwelling elderly persons. Over 12-week period, 36 participants underwent moderate assigned (n = 17, 60 mg/day) or placebo 19) group. At baseline at 12-weeks, we assessed body composition, grip strength, walking speed, leg functions, knee pain scores. Following skeletal mass, segmental mass (right arm, left trunk) score right were significantly improved group, while there was no change parameters had worsened Grip strength better side increased only These results suggest combined with increase upper reduce pain, could be effective for preventing mobility-related disability Clinical registration number: UMIN000017207.