Early findings in a pilot study of anterior cervical interbody fusion in which recombinant human bone morphogenetic protein–2 was used with poly(L-lactide-co-D,L-lactide) bioabsorbable implants

• DOI: 10.3171/foc.2004.16.3.7
• Publication Date: 2008-01-24T12:02:49Z
• Authors: Todd H. Lanman; Thomas J. Hopkins
• Keywords: Demineralized bone matrix

The goal of this study was to assess the efficacy bioabsorbable interbody spacers in cervical spine fusion.The authors report on a prospective examination 20 patients with degenerative disc disease who underwent anterior fusion at 28 total levels. used Infuse bone graft (that is, recombinant human morphogenetic protein-2 applied an absorbable collagen sponge and contained within Cornerstone-HSR spacer. Multiple-level fusions were performed 30% these patients. At 3 months postfusion, radiographs computerized tomography scans demonstrated bridging 100% Improvement from baseline scores physical functioning, mental health, bodily pain postoperatively according results Short Form-36 Version 2 health survey. There no device-related complications.The series indicate that use as spacer combination may be alternative treatment for fusion.