Relationship between body and brain temperature in traumatically brain-injured rodents

• DOI: 10.3171/jns.1991.74.3.0492
• Publication Date: 2009-05-19T16:16:04Z
• Authors: Ji Y. Jiang; Bruce G. Lyeth; Guy L. Clifton; Larry W. Jenkins; Robert J. Hamm; Ronald L. Hayes
• Keywords: Rectal temperature

✓ Recent work has shown that mild to moderate levels of hypothermia may profoundly reduce the histological and biochemical sequelae cerebral ischemic injury. In present study, authors examined effect fluid-percussion injury on brain temperature in anesthetized rats anesthesia uninjured rats. The relationship between brain, rectal, temporalis muscle temperatures during normothermia, hypothermia, hyperthermia was studied following a magnitude (2.10 2.25 atmospheres) results showed mean 10 injured rats, 21 unanesthetized (± standard error mean) 36.04° ± 0.20°C, 36.30° 0.08°C, 37.95° 0.09°C, respectively. There no significant difference under general (p > 0.05). absence injury, significantly lower than < 0.001). brain-injured correlated well with over 30° 40°C range, even when rapidly changed induction or (r = 0.9986, p 0.0001). contrast, rectal varied inconsistently from temperature. These observations indicated that: 1) itself does not influence this model; 2) alone decreases producing protection 3) external monitoring can provide reliable indirect measure course experimental believe it is essential monitor control studies