Histological yield, complications, and technological considerations in 114 consecutive frameless stereotactic biopsy procedures aided by open intraoperative magnetic resonance imaging

• DOI: 10.3171/jns.2002.97.2.0354
• Publication Date: 2009-05-13T17:45:03Z
• Authors: René L. Bernays; Spyros S. Kollias; Nadia Khan; Sebastian Brandner; Sonja Meier; Yasuhiro Yonekawa
• Keywords: Stereotactic biopsy

The authors undertook a prospective study of frameless, magnetic resonance (MR)-guided stereotactic brain biopsy procedures performed with the aid an open MR system. Morbidity and mortality rates, frequency postoperative hemorrhage, histological yield were evaluated, as well size location lesions under investigation.During period 51 months (July 1996-November 2000), 114 consecutive frameless intraoperative system to investigate supratentorial in 113 patients. median volume was 33.5 cm3, 31.9% deep seated. All samples comprised pathological tissue 111 (97.4%) specific neuropathological diagnosis made. A follow-up computerized tomography (CT) scan obtained on 1st day all patients evaluate complications. In two cases (1.8%), hemorrhage found CT scans, no neurological worsening seen three patients; it transient them one (0.9%) subsequent emergency craniotomy necessary because increased edema. There infections, but there death (0.9%)Open imaging transforms blind conventional procedure into visually controlled that is adaptable dynamic anatomical changes. Routine postprocedural makes scanning obsolete. This largest reported series MR-guided shows results are at least comparable those reports larger sampling. mean time 60 minutes including planning, this method produced low morbidity complication rates high yield.