Antibiotics Use among Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

• DOI: 10.31729/jnma.7512
• Publication Date: 2022-06-01T17:40:21Z
• Authors: Ushab Rana Mohsin; Nabin Simkhada; Bishnu Deep Pathak; Bishal Dhakal; Binaya Subedi; Dilip Thapa; Bishnu Prasad Shr...; Om Prakash Tandon; Sanjaya Shrestha; Shriya Sharma; Aakriti Adhikari
• Keywords: Medicine (General); Anti-Bacterial Agents; 3. Good health; Hospitalization; Tertiary Care Centers; Pulmonary Disease, Chronic Obstructive; 03 medical and health sciences; R5-920; Cross-Sectional Studies; 0302 clinical medicine; anti-bacterial agents; chronic obstructive pulmonary disease; guideline adherence.; Humans; Original Article

Introduction: Acute exacerbation of chronic obstructive pulmonary disease is a life-threatening condition triggered by infections or non-infectious agents. Antibiotics use in such cases prevents severe deterioration and treatment failure. Past studies have shown inappropriate use of antibiotics in different health care settings. The objective of this study was to find out the prevalence of antibiotics use in patients with acute exacerbation of chronic obstructive pulmonary disease in the Department of Internal Medicine of a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients with acute exacerbation of Chronic Obstructive Pulmonary Disease admitted to Department of Internal Medicine of a tertiary care centre from 12th February, 2022 to 15th April, 2022 after taking ethical clearance from Institutional Review Committee (Reference number: 417). Convenience sampling was done. Data analysis was done using the Statistical Package for the Social Sciences version 23.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data along with median and interquartile range for continuous data. Results: The prevalence of antibiotics use among study participants was 106 (98.15%) (95.61-100 at a 95% Confidence Interval). Penicillin 82 (75.93%) was the most commonly used antibiotics group. Conclusions: The use of antibiotics in acute exacerbation of chronic obstructive pulmonary disease was higher as compared to other similar studies.