MR Imaging Findings in Patients with Secondary Intracranial Hypertension

• DOI: 10.3174/ajnr.a2463
• Publication Date: 2011-04-21T22:21:28Z
• Authors: A.C. Rohr; C. Riedel; M.-C. Fruehauf; A. van Baalen; T. Bartsch; J. Hedderich; K. Alfke; L. Doerner; O. Jansen
• Keywords: Adult; Male; Adolescent; Intracranial Hypotension; Brain; Reproducibility of Results; Magnetic Resonance Imaging; Sensitivity and Specificity; 3. Good health; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Child, Preschool; Humans; Female; Child

<h3>BACKGROUND AND PURPOSE:</h3> IH can alter the configuration of anatomic structures central nervous system. We determined sensitivity and specificity MR imaging to detect these changes in patients with secondary IH. <h3>MATERIALS METHODS:</h3> Patients (<i>n</i> = 36) were prospectively investigated matched 36 controls. images evaluated for elongation edema optic nerves, protrusion disc, flattening posterior sclera, height pituitary gland, width nerve sheath. On MRV, we recorded venous sinus abnormalities measured luminal superior ophthalmic veins. A grading score was introduced define cranial outflow obstruction. <h3>RESULTS:</h3> Cranial obstruction ONS hydrops most valid signs indicating a 94% 92% 100% 89%, respectively. Sensitivities specificities 56% 97% reduced height, 64% 78% 31% widening veins, 33% disc protrusion, 14% edema, 6% nerve. At least 2 findings could be demonstrated each patient but none The number positive correlated CSF pressure (<i>r</i> 0.62, <i>P</i> .01). <h3>CONCLUSIONS:</h3> combination orbital MRV highly sensitive specific diagnosis