4D Digital Subtraction Angiography: Implementation and Demonstration of Feasibility

• DOI: 10.3174/ajnr.a3529
• Publication Date: 2013-04-26T03:11:23Z
• Authors: B. Davis; K. Royalty; M. Kowarschik; C. Rohkohl; E. Oberstar; B. Aagaard-Kienitz; D. Niemann; O. Ozkan; C. Strother; C. Mistretta
• Keywords: Digital subtraction angiography; Temporal resolution; Rotational angiography; Subtraction

<h3>BACKGROUND AND PURPOSE:</h3> Conventional 3D-DSA volumes are reconstructed from a series of projections containing temporal information. It was our purpose to develop technique which would generate fully time-resolved vascular having better spatial and resolution than that is available with CT or MR angiography. <h3>MATERIALS METHODS:</h3> After single contrast injection, the mask fill rotation subtracted create projections. With use these projections, conventional conebeam reconstruction generated (conventional 3D-DSA). This used constrain individual 3D volumes, incorporate information acquired (4D-DSA). <h3>RESULTS:</h3> Typically, 30 per second currently flat detector systems, factor ∼200 increase over achievable multiple gantry rotations. Dynamic displays viewable any angle. Good results have been obtained by using both intra-arterial intravenous injections. <h3>CONCLUSIONS:</h3> feasible commercially angiographic systems clinically practical injection protocols. The signal-to-noise ratio time frames largely determined constraining image not reconstruction. exceed CTA MRA, small vessel increased relative 2D-DSA due maximum intensity