Synthetic MRI in the Detection of Multiple Sclerosis Plaques

• DOI: 10.3174/ajnr.a5012
• Publication Date: 2016-12-08T21:55:24Z
• Authors: A. Hagiwara; M. Hori; K. Yokoyama; M.Y. Takemura; C. Andica; T. Tabata; K. Kamagata; M. Suzuki; K.K. Kumamaru; M. Nakazawa; N. Takano; H. Kawasaki; N. Hamasaki; A. Kunimatsu; S. Aoki
• Keywords: Fluid-attenuated inversion recovery; Contrast-to-noise ratio

<h3>BACKGROUND AND PURPOSE:</h3> Synthetic MR imaging enables the creation of various contrast-weighted images including double inversion recovery and phase-sensitive from a single quantification scan. Here, we assessed whether synthetic is suitable for detecting MS plaques. <h3>MATERIALS METHODS:</h3> Quantitative conventional data on 12 patients with were retrospectively analyzed. T2-weighted, FLAIR, recovery, produced after T1 T2 values proton density. Double optimized each patient by adjusting TI. The number visible plaques was determined radiologist set these 4 types T1-weighted FLAIR images. Conventional 3D other available used as criterion standard. total acquisition time 7 minutes seconds that 6 29 lesion-to-WM contrast contrast-to-noise ratio calculated compared between <h3>RESULTS:</h3> detected 157 139, respectively (<i>P</i> = .014). superior to those .001 &lt; 0.001, respectively). <h3>CONCLUSIONS:</h3> enabled detection more than in comparable time. better