Optimization of Quantitative Dynamic Postgadolinium MRI Technique Using Normalized Ratios for the Evaluation of Temporomandibular Joint Synovitis in Patients with Juvenile Idiopathic Arthritis

• DOI: 10.3174/ajnr.a5424
• Publication Date: 2017-11-23T11:15:22Z
• Authors: P. Caruso; K. Buch; S. Rincon; R. Hakimelahi; Z.S. Peacock; C.M. Resnick; C. Foster; L. Guidoboni; T. Donahue; R. Macdonald; H. Rothermel; H.D. Curtin; L.B. Kaban
• Keywords: Dynamic Contrast-Enhanced MRI

<h3>BACKGROUND AND PURPOSE:</h3> MR imaging has been shown to be useful in the diagnosis of juvenile idiopathic arthritis temporomandibular joint. Prior approaches have relied mainly on subjective interpretation synovial enhancement as a marker for inflammation. Although, more recently, several attempts made quantify enhancement, these methods not taken into account dynamic characteristics joint and effect sampling time. Our aim was develop clinically feasible, reproducible, dynamic, contrast-enhanced technique quantitative assessment synovitis patients with study time evaluation synovitis. <h3>MATERIALS METHODS:</h3> This retrospective all who had coronal T1 3T through at our institution between January 1, 2015, July 8, 2016. Patients this cohort included those history control underwent other routine, clinical purposes. Synovial calculated each using 3 different types equations termed normalization ratios. The profiles generated by equation were studied determine which provided best discrimination affected unaffected joints, least susceptible errors, most feasible. <h3>RESULTS:</h3> A ratio (defined difference postgadolinium pregadolinium signal synovium) longus capitis susceptibility error, thought feasible method quantification Additional ratios did provide same level rates joints too temporally variable reliable use. <h3>CONCLUSIONS:</h3> We robust, gadolinium-enhanced arthritis.