Haemophilus influenzae Invasive Disease in the United States, 1994–1995: Near Disappearance of a Vaccine-Preventable Childhood Disease

• DOI: 10.3201/eid0402.980210
• Publication Date: 2009-08-24T14:28:24Z
• Authors: Kristine M. Bisgard; Annie Kao; John Leake; Peter M. Strebel; Bradley A. Perkins; Melinda Wharton
• Keywords: Hib vaccine; Disease Surveillance

We analyzed national Haemophilus influenzae (Hi) surveillance data from 1994 and 1995 to describe the epidemiology of Hi invasive disease among persons all ages. Serotype were available for 376 (56%) 669 reported cases children aged 4 years or younger; 184 (49%) H. type b (Hib). Among younger, incidence (per 100,000) was 1.8 in 1.6 (p < 0.05) 1995. Children 5 months younger had highest average annual rate Hib (2.2 per 100,000); 6 11 next (1.2 100,000)(p 0.05). Of 181 with whose age known, 85 (47%) too young (aged younger) have completed a primary series an Hib-containing vaccine. 83 known vaccination status who eligible receive older), 52 (63%) undervaccinated, remaining 31 (37%) which vaccine failed. older disease, lowest those 20 39 (0.15 100,000), 80 (2.26 100,000). older, serotype 1,372 (71%) 1,940 cases; 159 (28%) 568 due Hib.