Global Distribution of Mycobacterium tuberculosis Spoligotypes

• DOI: 10.3201/eid0811.020125
• Publication Date: 2012-06-27T05:35:52Z
• Authors: Ingrid Filliol; Jeffrey R. Driscoll; Dick van Soolingen; Barry N. Kreiswirth; Kristin Kremer; Georges Valétudie; Dang Duc Anh; Rachael Barlow; Dilip Banerjee; Pablo J. Bifani; Karin Brudey; Angel Cataldi; Robert C. Cooksey; Debby V. Cousins; Jeremy W. Dale; Odir A. Dellagostin; Francis Drobniewski; Guido Engelmann; Séverine Ferdinand; Deborah Gascoyne-...; Max Gordon; M. Cristina Gutie...; Walter H. Haas; Herre Heersma; Gunilla Källenius; Eric Kassa-Kelembho; Tuija Koivula; Ho Minh Ly; Athanasios Makris...; Caterina Mammina; Gerald Martin; Peter Moström; Igor Mokrousov; Valérie Narbonne; Olga Narvskaya; Antonino Nastasi; Sara Ngo Niobe-Ey...; Jean W Pape; Voahangy Rasolofo...; Malin Ridell; M. Lucia Rossetti; Fritz Stauffer; Philip N. Suffys; Howard Takiff; Jeanne Texier-Mau...; Véronique Vincent; Jacobus H. de Waard; Christophe Sola; Nalin Rastogi
• Keywords: Mycobacterium tuberculosis complex

Abstract We present a short summary of recent observations on the global distribution major clades Mycobacterium tuberculosis complex, causative agent tuberculosis. This was defined by data-mining an international spoligotyping database, SpolDB3. database contains 11,708 patterns from as many clinical isolates originating more than 90 countries. The spoligotypes were clustered into 813 shared types. A total 1,300 orphan (clinical showing unique spoligotype) also detected.