Eighth Major Clade for Hepatitis Delta Virus

• DOI: 10.3201/eid1209.060112
• Publication Date: 2011-11-21T17:07:37Z
• Authors: Frederic Le Gal; Elyanne Gault; Marie-Pierre Ripault; Jeanne Serpaggi; Jean-Claude Trinchet; Emmanuel Gordien; Paul Deny
• Keywords: emerging virus; 0301 basic medicine; DNA, Complementary; Hepatitis D, Chronic; Molecular Sequence Data; Deltavirus genus; Infectious and parasitic diseases; RC109-216; molecular epidemiology; 03 medical and health sciences; Hepatitis delta virus; Humans; Phylogeny; phylogenetic analysis; R; Dispatch; Genetic Variation; Sequence Analysis, DNA; Emigration and Immigration; Senegal; 3. Good health; Cote d'Ivoire; Medicine; RNA, Viral; chronic hepatitis; France; Hepatitis Delta Virus

Hepatitis delta virus is the only representative of the Deltavirus genus, which consists of 7 differentiated major clades. In this study, an eighth clade was identified from 3 distinct strains. Deltavirus genetic variability should be considered for diagnostic purposes. Clinical consequences of the diversity have yet to be evaluated.