Fourth Human Parechovirus Serotype

• DOI: 10.3201/eid1210.051647
• Publication Date: 2011-11-14T15:16:59Z
• Authors: Kimberley S.M. Be...; Janke Schinkel; Manon E. Luken; Peter J.M. van de...; Matthias F.C. Bee...; Negassi Menelik; Hans L. Zaaijer; Christina M.J.E. ...; Marcel G.H.M. Beld; Katja C. Wolthers
• Keywords: 0301 basic medicine; Picornaviridae Infections; Base Sequence; Genotype; phylogenetic analysis; R; Dispatch; Infant, Newborn; Parechovirus; Infectious and parasitic diseases; RC109-216; Genome, Viral; SimPlot analysis; HPeV serotype; 3. Good health; 03 medical and health sciences; neutralization assay; Neutralization Tests; New human parechovirus genotype; Medicine; Humans; full length genotyping

We identified a novel human parechovirus (HPeV) type (K251176-02) from a neonate with fever. Analysis of the complete genome showed K251176-02 to be a new HPeV genotype. Since K251176-02 could not be neutralized with antibodies against known HPeV serotypes 1-3, it should be classified as a fourth HPeV serotype.