Clostridium difficile PCR Ribotypes in Calves, Canada

• DOI: 10.3201/eid1211.051581
• Publication Date: 2011-11-02T13:53:39Z
• Authors: Alexander Rodrigu...; Henry R. Stämpfli; Todd Duffield; Andrew S. Peregrine; Lise A. Trotz-Wil...; Luis G. Arroyo; Jon S. Brazier; J. Scott Weese
• Keywords: Clostridium Infections; Ribotyping

We investigated Clostridium difficile in calves and the similarity between bovine human C. PCR ribotypes by conducting a case-control study of from 102 dairy farms Canada. Fecal samples 144 with diarrhea 134 control were cultured for tested an ELISA toxins A B. was isolated 31 278 calves: 11 (7.6%) 20 (14.9%) controls (p = 0.009). Toxins detected calf feces 58 (56.8%) farms, 57 (39.6%) diarrhea, 28 (20.9%) 0.0002). ribotyping isolates showed 8 distinct patterns; 7 have been identified humans, 2 which associated outbreaks severe disease (PCR types 017 027). may be cattle reservoirs humans.