Recombination in Vaccine and Circulating Strains of Porcine Reproductive and Respiratory Syndrome Viruses

• DOI: 10.3201/eid1512.090390
• Publication Date: 2009-11-26T00:37:54Z
• Authors: Bin Li; Liurong Fang; Zuofei Xu; Suyan Liu; Jianfeng Gao; Yunbo Jiang; Huanchun Chen; Shaobo Xiao
• Keywords: Recombination, Genetic; China; Swine; R; Dispatch; dispatch; Viral Vaccines; Infectious and parasitic diseases; RC109-216; 04 agricultural and veterinary sciences; 3. Good health; 0403 veterinary science; Open Reading Frames; Porcine reproductive and respiratory syndrome virus; pathogenicity; Medicine; Animals; natural recombination; viruses; Porcine respiratory and reproductive syndrome virus; Phylogeny

Em2007, a porcine reproductive and respiratory syndrome virus (PRRSV) variant with a unique 68 aa deletion in Nsp2, was recently isolated in China. Phylogenetic and molecular evolutionary analyses indicated that Em2007 is a natural recombinant between a vaccine strain of PRRSV and circulating virus. We also tested its pathogenicity in piglets.