Picornavirus Salivirus/Klassevirus in Children with Diarrhea, China

• DOI: 10.3201/eid1608.100087
• Publication Date: 2010-08-05T00:17:51Z
• Authors: Tongling Shan; Chunmei Wang; Li Cui; Ying Yu; Eric Delwart; Wei Zhao; Caixia Zhu; Daoliang Lan; Xiuqiang Dai; Xiuguo Hua
• Keywords: Diarrhea; China; Molecular Sequence Data; diarrhea; Infectious and parasitic diseases; RC109-216; Picornaviridae; Polymerase Chain Reaction; Feces; 03 medical and health sciences; Humans; viruses; Child; Phylogeny; 0303 health sciences; Picornaviridae Infections; Base Sequence; R; Dispatch; Salivirus/Klassevirus; dispatch; Sequence Analysis, DNA; 3. Good health; Child, Preschool; DNA, Viral; Medicine; 5' Untranslated Regions

To learn more about salivirus/klassevirus, we tested feces of children with diarrhea in China during 2008-2009. We isolated the virus from 9/216 diarrhea samples and 0/96 control samples. The nearly full polyprotein of 1 isolate, SH1, showed 95% identity with a salivirus from Nigeria, indicating widespread distribution and association with diarrhea.