Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
Male
0301 basic medicine
0303 health sciences
mouse lemur
Prions
[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
R
Dispatch
Brain
Infectious and parasitic diseases
RC109-216
Animal Feed
BSE
3. Good health
prion
prions and related diseases
L-type BSE
Encephalopathy, Bovine Spongiform
03 medical and health sciences
Medicine
Animals
Cattle
Female
bovine spongiform encephalopathy
Cheirogaleidae
DOI:
10.3201/eid1801.111092
Publication Date:
2012-01-06T19:55:29Z
AUTHORS (8)
ABSTRACT
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue. After neurologic symptoms appeared, transmissibility of the disease by both inoculation routes was confirmed by detection of disease-associated prion protein in samples of brain tissue.
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CITATIONS (38)
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