Molecular Epidemiology of Laguna Negra Virus, Mato Grosso State, Brazil

• DOI: 10.3201/eid1806.110948
• Publication Date: 2012-05-03T13:54:23Z
• Authors: Elizabeth S. Trav...; Daniele B.A. Mede...; Márcio R.T. Nunes; Darlene B. Simith; Armando de S. Per...; Mauro R. Elkhoury; Elizabeth Davi Sa...; Marília Lavocat; Aparecido A. Marques; Alba V.G. Via; Vânia A. Kohl; Ana C.P. Terças; Paulo D`Andrea; Cibele R. Bonvícino; Elba R. Sampaio d...; Pedro F.C. Vascon...
• Keywords: Orthohantavirus; Infectious and parasitic diseases; RC109-216; Hantavirus Pulmonary Syndrome; hantavirus; Rodent Diseases; respiratory infections; Mice; 03 medical and health sciences; 0302 clinical medicine; Animals; Humans; Phylogeny; Laguna Negra; Likelihood Functions; Arvicolinae; R; Dispatch; Genetic Variation; Bayes Theorem; Nucleocapsid Proteins; 3. Good health; rodents; Viruses; Medicine; hantaviral pulmonary syndrome; Brazil; Multilocus Sequence Typing

We associated Laguna Negra virus with hantavirus pulmonary syndrome in Mato Grosso State, Brazil, and a previously unidentified potential host, the Calomys callidus rodent. Genetic testing revealed homologous sequencing in specimens from 20 humans and 8 mice. Further epidemiologic studies may lead to control of HPS in Mato Grosso State.