Cross-Neutralization between Human and African Bat Mumps Viruses

• DOI: 10.3201/eid2204.151116
• Publication Date: 2016-02-24T21:58:41Z
• Authors: Hiroshi Katoh; Toru Kubota; Toshiaki Ihara; Ken Maeda; Makoto Takeda; Minoru Kidokoro
• Keywords: Mumps virus; Mumps vaccine

Abstract Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat glycoproteins. These viruses showed replication kinetics similar MuV cultured cells were neutralized efficiently by serum from healthy humans.