Effects of Zika Virus Strain andAedesMosquito Species on Vector Competence

• DOI: 10.3201/eid2307.161633
• Publication Date: 2017-04-21T14:59:16Z
• Authors: Alexander T. Ciota; Sean M. Bialosuknia; Steven D. Zink; Matthew Brecher; Dylan J. Ehrbar; Madeline N. Morri...; Laura D. Kramer
• Keywords: Zika Virus; Aedes albopictus; Infectivity

In the Western Hemisphere, Zika virus is thought to be transmitted primarily by Aedes aegypti mosquitoes. To determine extent which Ae. albopictus mosquitoes from United States are capable of transmitting and influence dose, strain, mosquito species on vector competence, we evaluated multiple doses representative strains in Virus preparation (fresh vs. frozen) significantly affected infectivity We calculated 50% infectious 6.1-7.5 log 10 PFU/mL; minimum infective dose was 4.2 PFU/mL. were more susceptible infection than mosquitoes, but transmission efficiency higher for indicating a barrier Results suggest that, although relatively inefficient overall dependent strain species, could become major vectors Americas.