blaCTX-M-27–EncodingEscherichia coliSequence Type 131 Lineage C1-M27 Clone in Clinical Isolates, Germany

• DOI: 10.3201/eid2310.170938
• Publication Date: 2017-08-31T12:03:35Z
• Authors: Hiren Ghosh; Swapnil Doijad; Linda Falgenhauer; Moritz Fritzenwanker; Can Imirzalioglu; Trinad Chakraborty
• Keywords: 0301 basic medicine; Livestock; ST131; Gene Expression; Infectious and parasitic diseases; RC109-216; beta-Lactamases; extended-spectrum β-lactamases; 03 medical and health sciences; Germany; Research Letter; Escherichia coli; Animals; Humans; Alleles; Escherichia coli Infections; Phylogeny; Escherichia coli Proteins; Incidence; CTX-M-27; R; C1-M27; Pets; Clone Cells; 3. Good health; ESBL; Food Microbiology; Medicine; Water Microbiology; Multilocus Sequence Typing; Plasmids

We examined extended-spectrum β-lactamase-producing isolates from livestock, humans, companion animals, food, and the environment during 2009-2016 in Germany for the presence of CTX-M-27 allele within Escherichia coli sequence type (ST) 131. E. coli ST131 C1-M27 was exclusively present in humans; its incidence increased from 0% in 2009 to 45% in 2016.