Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

• DOI: 10.3201/eid2311.161443
• Publication Date: 2017-10-02T12:43:35Z
• Authors: Yi-Chin Fan; Jen-Wei Lin; Shu-Ying Liao; Jo-Mei Chen; Yi-Ying Chen; Hsien-Chung Chiu; Chen-Chang Shih; Chi-Ming Chen; Ruey-Yi Chang; Chwan-Chuen King; Wei-June Chen; Yi-Ting Ko; Chao-Chin Chang; Shyan-Song Chiou
• Keywords: Adult; Encephalitis Virus, Japanese; Male; 0303 health sciences; Genotype; Virulence; genotype; R; Dispatch; Taiwan; mosquitoborne; Infectious and parasitic diseases; RC109-216; Middle Aged; 3. Good health; Japanese encephalitis virus; 03 medical and health sciences; flavivirus; GI JEV; GIII JEV; Medicine; Humans; Female; Encephalitis, Japanese

The virulence of genotype I (GI) Japanese encephalitis virus (JEV) is under debate. We investigated differences in the virulence of GI and GIII JEV by calculating asymptomatic ratios based on serologic studies during GI- and GIII-JEV endemic periods. The results suggested equal virulence of GI and GIII JEV among humans.