African Histoplasmosis in HIV-Negative Patients, Kimpese, Democratic Republic of the Congo

• DOI: 10.3201/eid2411.180236
• Publication Date: 2018-09-25T13:05:20Z
• Authors: Nestor Pakasa; Asaf Biber; Samuel Nsiangana; Désiré Imposo; Ernest Sumaili; Hypolite Muhindo; Maria J. Buitrago; Iris Barshack; Eli Schwartz
• Keywords: Adult; Male; 0301 basic medicine; Adolescent; Histoplasma; Infectious and parasitic diseases; RC109-216; Histoplasma capsulatum var. duboisii; Young Adult; 03 medical and health sciences; Humans; Child; Histoplasmosis; histoplasmosis; R; Dispatch; Kimpese; Middle Aged; 16. Peace & justice; Immunohistochemistry; 3. Good health; Child, Preschool; Democratic Republic of the Congo; African histoplasmosis; Medicine; Female; Human medicine; fungi

We describe a case series of histoplasmosis caused by Histoplasma capsulatum var. duboisii during July 2011-January 2014 in Kimpese, Democratic Republic of the Congo. Cases were confirmed by histopathology, immunohistochemistry, and reverse transcription PCR. All patients were HIV negative. Putative sources for the pathogen were cellar bats and guano fertilizer exploitation.