Seroprevalence and Risk Factors Possibly Associated with Emerging Zoonotic Vaccinia Virus in a Farming Community, Colombia

• DOI: 10.3201/eid2512.181114
• Publication Date: 2019-11-14T22:44:26Z
• Authors: Ashley Styczynski; Jillybeth Burgado; Diana Walteros; José Usme-Ciro; Katherine Laiton; Alejandra Pinilla...; Yoshinori Nakazawa; Christina Chapman; Whitni Davidson; Matthew Mauldin; Clint Morgan; Juan Martínez-Cerón; Edilson Patiña; Leidy Laura López...; Claudia Patricia ...; Anyely Eliana Cru...; Gina Paez Olaya; Carlos Elkin Riveros; Diana Yaneth Cepeda; Leydi Acosta Lopez; Daniela Gomez Esp...; Faiber Antonio Gu...; Yu Li; P.S. Satheshkumar; Mary Reynolds; Martha Gracia-Romero; Brett Petersen
• Keywords: Seroprevalence; Zoonotic disease

In 2014, vaccinia virus (VACV) infections were identified among farmworkers in Caquetá Department, Colombia; additional cases Cundinamarca Department 2015. VACV, an orthopoxvirus (OPXV) used the smallpox vaccine, has caused sporadic bovine and human outbreaks countries such as Brazil India. response to emergence of this disease Colombia, we surveyed collected blood from 134 household members 56 farms Department. We tested serum samples for OPXV antibodies correlated risk factors with seropositivity by using multivariate analyses. Fifty-two percent had antibodies; percentage decreased 31% when excluded persons who would have been eligible vaccination. The major municipality, age, vaccination scar, duration time working on a farm, animals having vaccinia-like lesions. This investigation provides evidence possible VACV zoonosis South America.