Epidemiologic History and Genetic Diversity Origins of Chikungunya and Dengue Viruses, Paraguay

• DOI: 10.3201/eid2705.204244
• Publication Date: 2021-04-27T11:42:56Z
• Authors: Tiago Gräf; Cynthia Vazquez; Marta Giovanetti; Fernanda de Bruyc...; Vagner Fonseca; Ingra Morales Claro; Jaqueline Goes de...; Andrea Gómez; Joilson Xavier; Marcos Cesar Lima...; Shirley Villalba; Juan Torales; Maria Liz Gamarra; Julien Thézé; Ana Maria Bispo d...; Vasco Azevedo; Tulio de Oliveira; Leticia Franco; Carlos F. Campelo...; Sandra Irala; Edward Charles Ho...; Jairo Andrés Ménd...; Luiz Carlos Junio...
• Keywords: Viral evolution

Abstract Paraguay has been severely affected by emergent Zika and chikungunya viruses, dengue virus is endemic. To learn more about the origins of genetic diversity epidemiologic history these viruses in Paraguay, we deployed portable sequencing technologies to strengthen genomic surveillance determine evolutionary epidemic arthropod-borne (arboviruses). Samples stored at National Central Laboratory were sequenced subjected phylogenetic analysis. Among 33 genomes generated, identified 2 genotypes serotypes that circulated during 2014–2018; main source lineages was estimated be Brazil. The inferred our analyses precisely matched available travel patients. approach used valuable for describing arboviruses can evolution future arbovirus outbreaks.